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BRD 8430
CAS No. 1482499-16-0
BRD 8430( BRD8430 )
Catalog No. M12045 CAS No. 1482499-16-0
BRD 8430 is a potent, selective class I HDAC inhibitor (HDAC1>2 >3) with IC50 of 69 nM/560/1300 nM for HDAC1/2/3, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameBRD 8430
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NoteResearch use only, not for human use.
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Brief DescriptionBRD 8430 is a potent, selective class I HDAC inhibitor (HDAC1>2 >3) with IC50 of 69 nM/560/1300 nM for HDAC1/2/3, respectively.
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DescriptionBRD 8430 is a potent, selective class I HDAC inhibitor (HDAC1>2 >3) with IC50 of 69 nM/560/1300 nM for HDAC1/2/3, respectively; shows no activity against other HDACs; decreases viability and induces differentiation of neuroblastoma cell lines.
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In Vitro——
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In Vivo——
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SynonymsBRD8430
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PathwayCell Cycle/DNA Damage
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TargetHDAC
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RecptorHDAC
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Research Area——
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Indication——
Chemical Information
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CAS Number1482499-16-0
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Formula Weight573.738
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Molecular FormulaC33H43N5O4
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical NameN-(2-aminophenyl)-4-[[[(2R,3S)-9-(dimethylamino)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-2,3,4,7-tetrahydro-1,5-benzoxazonin-2-yl]methyl-methylamino]methyl]benzamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Frumm SM, et al. Chem Biol. 2013 May 23;20(5):713-25.
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